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Therefore, it is important to consistently use sun protection to manage melasma and prevent further pigmentation issues

An increase in the concentration of cystine is dangerous for the cell, since cystine promotes the formation of disulfide bridges in proteins, which affects their functioning [27]

Similarly, the GlyT1 inhibition has been investigated for its potential to reduce alcohol consumption

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For this reason, we emphasizes informed consent, realistic expectations, and careful patient selection

By acknowledging the active role of glial cells, securing robust biomarkers, and designing multimodal, personalized strategies, the field can move closer to genuine disease modification