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ChiE displaying inhibitory activity on all three pathways clearly protects susceptible spirochetes from complement-mediated killing comparable to ChiB, ChiC, and ChiD, however, the ChiE-producing strain was killed by human serum (Fig

Accordingly, other aspects of AD pathology, more closely related to the clinical symptoms of AD are currently investigated like the already mentioned synaptic deficits and other measures of neurodegeneration and their relationship to impairment of mitochondrial function

Due to decreased saliva production, patients have trouble eating, speaking, and swallowing 1, 2

These changes may also promote programmed cell death in activated fibroblasts and other pro-fibrotic cells, thereby reducing fibrogenic activity

ProteiNorm (Graw et al., 2020) was used to evaluate the quality of MS2 intensities and variance stabilizing normalization was applied (Huber et al., 2002)

Toupance, B