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Contraindications: Uncontrolled asthma Known hypersensitivity to pilocarpine When miosis is undesirable Side Effects: The most frequent adverse experiences are a consequence of the expected pharmacologic effects of pilocarpine & include headache, sweating, flushing, increased urinary frequency

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IRI is the most common pathogenesis that induces AKI in clinics, and generally occurs in the cerebrum, intestines, heart, lungs, and liver, during which process ferroptosis plays a vital role