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There appears to be a synergistic effect on modulation of alcohol and ingestion of phenytoin in incrementing serum GT levels

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Oncotarget 8, 81649

Studies have highlighted the role of persistent fibrosis in aged tissues, where myofibroblasts in injured tissues of aged mice acquire a sustained senescent and apoptosis-resistant phenotype, exacerbating fibrosis (Hecker et al., 2014)