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clinical studies in children noted a small percentage of patients developed hypothyroidism during GH/GHRH therapy and required thyroid hormone replacement

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CERTIFICATE OF ANALYSIS Product name 5-amino-1-methylquin olin-1-iumiodide CAS NO 42464-96-0 Molecular formula C10H11IN2 Molecular weight 286.11 Quantity Test based on enterprise standard Test Item Specification Result Appearance Reddish brown solid powder Conforms PurityHNMR 98.0% Conforms Purity(HPLC) 98.0% 99.4% 400MHz 1H Consistent Consistent MS 159.21.0 158.2 Storage In an air tight container,protected from light at temperature 2-8

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PubMed PMID: 4696188

Correction of the DNA synthesis defect in vitamin B12 deficiency by tetrahydrofolate: evidence in favour of the methyl-folate trap hypothesis as the cause of megaloblastic anaemia in vitamin B12 deficiency