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Individual variation : People may respond differently to supplements based on their underlying health status, though controlled studies examining formulation-specific effects on anxiety are lacking

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They are generally not recommended during pregnancy or breastfeeding, for people with a known allergy to any component of the formulation, or for those with certain medical conditions

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For a more budget-friendly solution, you could consider at-home injection kits, which are often a cost-effective option for long-term use

Dissolved under the tongue, which allows some absorption through the oral mucosa and bypasses the stomach and intrinsic factor pathway