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Other Yale authors are Sa Rang Kim, Henry Heaton, and Lucy Y

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Great efforts have been made to devise strategies that enable drugs to cross the BBB

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GSSSG, another endogenous supersulfie donor, was shown to suppress LPS-induced inflammatory profiling in both human and mouse epithelial cells [124]

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Paulo, J.A

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Moreover, mice and rat models of traumatic brain injury (Yu et al., 2012) and cerebral ischemia (Kawabori and Yenari, 2015) result in neuro-inflammation, including increase in toll-like receptors (TLRs), microglial activation, and expression of pro-inflammatory enzymes (cyclo-oxygenase-2, COX-2) and cytokines (IL-1, TNF), in correlation with secondary cognitive defects comparable to TBI (Vincent et al., 2014) and vascular-related dementias (Kawabori and Yenari, 2015)

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