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Andreeff M, Battula VL, R-Y W, Chen Y, Ling X, Jacamo R, Spaeth E, Konoplev S, Burks J, Hazen A, Schober W, Lu H, Mak D, McQueen T, Shi Y, Tsao T, Zhou L, Ruvolo V, Ruvolo P, Benito J, Borthakur G, Duvvuri S, Klopp A, Mani S, Lang F, Zeng Z, Carter B, Kornblau S, Konopleva M, Marini F

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This article summarises published preclinical findings and analytical-quality considerations

Atp7b / mice recapitulate the main features of WD including accumulation of copper in the liver and extensive liver damage, which manifest in hepatitis, fibrosis, and the formation of cholangiocarcinoma 32