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American Journal of Physiology-Heart and Circulatory Physiology, 303(6), H703H711

H.NacarE.OnlenY.OzerB.et al (2011)

By pooling data, it increases statistical power and produces more reliable conclusions than any individual study

It remains unclear whether pharmacological stimulation of IGF-1/PI3K/Akt signaling attenuates immobilization- or unloading-induced muscle atrophy

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For the treatment of the atherosclerosis, statins are commonly used due to their excellent efficacy in minimizing the LDL level in the serum and inhibiting the vascular risk, but the continuous use of statins lead to more side effects