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Repeated elastography was performed by the same operator, and statistical comparisons were tested with Wilcoxon-rank test for paired samples

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Lipohypertrophy disrupts absorption and produces inconsistent drug levels

447 Furthermore, astrocytic atrophy and reduced presence of astrocytes around synapses affects synaptic maintenance, glutamate homoeostasis, and K + buffering thus affecting neuronal excitability and limiting synaptic plasticity