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E., Grant, G

At the cellular level, ethanol induces activation of inflammatory and degenerative processes in the brain [88, 89]

By impeding NF-B-dependent transcription of inflammatory mediators such as IL-6 and monocyte chemoattractant protein-1(MCP-1), these agents may contribute to re-establishing a more tolerogenic immune microenvironment (83)

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In particular embodiments, methods of the present invention further comprise a step of neutralizing at least some of the surface charges on the lipid portions of the lipid-nucleic acid compositions

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