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Liu C, Zhou X, Pan Y, Liu Y, Zhang Y

(iii) U0126 (15 mg/kg)

The reciprocal tumor-adipocyte crosstalk not only sustains the high energy needs of proliferative cancer cells but also fosters an immunosuppressive and pro-inflammatory niche that favors tumor aggressiveness [7,27]

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In this review, based on the mechanisms of TBI and the properties of various biomaterials, we discuss the role of biomaterials and TE in regulating biochemical stress, anti-neuroinflammation, neuroprotection, and neural and vascular regeneration in TBI patients ( Figure 1 )