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In contrast, APAP-CYS was capable to induce only a mild impairment in HK-2 cells and APAP did not induce any significant changes in treated cells

doi: 10.1212/wnl.0000000000003936 121 KoepsellH

A key point of our study is our finding of a reduction of glutathione in NTG patients, suggesting that excessive oxidative stress may contribute to optic nerve damage and RGC loss independently of high IOP in glaucoma

The RasV12 upregulation and downregulation of Dlg and GFP in Drosophila can result in the tumorigenesis and increased metastasis of surrounding brain tissue