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PKC activation disrupts normal metabolism, leading to ATPase phosphorylation and metabolic disorders, including changes in VEGF and vasoconstriction, which affect pain perception

Testing should include: Comprehensive metabolic panel Gamma-glutamyltransferase if alcohol abuse is suspected, since heavy alcohol use is one of the most common causes of both large and small fiber neuropathy

Our food supplements do not contain any ingredients of animal origin

Gently cleanses without drying or irritating

This approach provides both the systemic gene expression modulation from injections and concentrated local delivery from topical application

Lower serum levels of PLP have been linked to diabetes incidence and progression, and vitamin B6s anti-glycation properties may help prevent complications of diabetes (Mascolo 2020)