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Studied for body-weight reduction Investigated in the phase 3 REDEFINE program for change in body weight in adults with obesity, with and without type 2 diabetes

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In a clinical trial (NCT01834989), IGF-1 was locally infused to improve the tendon structure in patients with patellar tendinopathy, but the overall results indicated no therapeutic benefit for tendon healing associated with local IGF-1 injection [444]

Exogenous sources of free radicals include environmental factors such as ultraviolet (UV) radiation, ionizing radiation, tobacco smoke, pollution, and exposure to certain chemicals and drugs [24]

Melatonin signal transduction and mechanism of action in the central nervous system: using the rabbit cortex as a model

Callus cultured on ZnONP-containing media showed a slight reduction in MDA content at 2 mg L -1 (14.700.16 nM g -1 FW), although its levels increased with higher concentrations