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In contrast, fetal muscle showed no changes in mitochondrial activity but displayed reduced expression of genes involved in fat metabolism and energy production, suggesting early transcriptional changes that could affect postnatal muscle energy utilization (Safain et al., 2025)

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Anabolic androgenic steroids in orthopaedic surgery: current concepts and clinical applications

Mitochondria also host antioxidant enzymes such as superoxide dismutase (SOD) and catalase as the first line of defense against ROS by converting superoxide to H 2 O 2 and subsequently to water

Once-weekly cagrilintide for weight management in people with overweight and obesity: a multicentre, randomised, double-blind, placebo-controlled, dose-finding phase 2 trial

Though TRT is beneficial in many ways, like many other therapies, it comes with some side effects