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This procedure involved removing the supernatant and resuspending the mitochondrial pellet in an isolation buffer of 250 mM sucrose, 0.5 mM EDTA, and 10 mM Tris-HCl to achieve a final protein concentration of 20-25 mg/ml [2]
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Teelken et al., 1989), while L-threo-DOPS increases CSF NE levels (Tohgi et al., 1990, 1993d)
Another randomized study in 44 breast cancer patients receiving paclitaxel reported lower levels of motor and sensory peripheral neuropathy in patients who wore frozen gloves/socks from 15 minutes before chemotherapy until 15 minutes after chemotherapy (Shigematsu 2020)