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Rheumatic heart disease

Carbamazepine: The oral clearance of alprazolam (given in a 0.8 mg single dose) was increased from 0.900.21 mL/min/kg to 2.130.54 mL/min/kg and the elimination T1/2 was shortened (from 17.14.9 to 7.71.7 hour) following administration of 300 mg per day carbamazepine for 10 days [see Drug Interactions (7.2)]

P.KurzE.MishraA.et al (2018)

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Thank you to our sponsors AG1 (Athletic Greens): Levels: WHOOP: Eight Sleep: InsideTracker: Supplements from Momentous For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Dr

Abais JM, Zhang C, Xia M, Liu Q, Gehr TW, Boini KM et al