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Thymosin beta 4 ophthalmic solution for dry eye: a randomized, placebo-controlled, Phase II clinical trial

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15,16 A classic diagnostic feature is the urinary coproporphyrin isomer pattern: patients with DJS typically have normal total urine coproporphyrin levels, but markedly increased coproporphyrin I isomer levels, constituting over 80% of total urinary coproporphyrins