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The radiation-sensitization effects of these compounds are currently being investigated

The seventh report of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressure: the JNC 7 report

First, the paracellular pathway: IFN- and TNF- activate the NF-B signaling pathway, leading to downregulation of tight junction proteins (claudin-5, occludin, and ZO-1) in cerebrovascular endothelial cells and triggering caspase-3/9-mediated tight junction remodeling