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Although only IL-1-induced cyclo-oxygenase 2 (COX2) production and IL-8 secretion could be attenuated by the ERK1/2-specific inhibitor PD98059, both TNF- and IL-1 activate ERK and induce the expression of IL-8 and IL-6 [128]

4 Molecular mechanisms of the activation of pro-inflammatory response caused by bacterial invasion Dysbacteriosis of the gut microbiota can lead to disruption of intestinal barrier function and immune homeostasis

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A mouse model of retinal ischemia-reperfusion injury through elevation of intraocular pressure

Plant Physiol 174:16481668 Leuci R, Brunetti L, Laghezza A, Loiodice F, Tortorella P, Piemontese L (2020) Importance of biometals as targets in medicinal chemistry: An overview about the role of Zinc (II) chelating agents