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Regulation of neutrophil degranulation and cytokine secretion: a novel model approach based on linear fitting

Metabolic transformation has a profound effect on anti-inflammatory activity of flavonoids such as quercetin: lack of association between antioxidant and lipoxygenase inhibitory activity

Furthermore, a recent study unveiled a significant upregulation of 4-HNE expression in lung fibroblasts isolated from PF patients, concomitant with a concurrent reduction in GPX4 levels and an elevation in 4-HNE expression observed in an in vivo model of bleomycin (BLM)-induced PF [59]