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However, there are no published clinical trials of the drug among people without these disorders

Activation of nicotine receptors on oral melanocytes by acetylcholine or by nicotine may bring about melanin hyperpigmentation [4, 6, 30]

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Materials and Methods This was a retrospective analysis of the clinical and histologic data of 14 patients diagnosed with atypical lentiginous nevus in the dermatology department of the Hospital General Universitario in Valencia between December 2007 and March 2009 (Table 1)