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However, considerable clinical problems on bone defect are so far unaddressed, with a remaining group of 10% to 20% of delayed or nonunion situations [2]

doi: 10.3389/fphys.2020.621226 Received 25 October 2020 Accepted 18 December 2020 Published 15 January 2021 Volume 11 - 2020 Edited by James P

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The success of using introduced cysteine residues for site-specific conjugation relies on the ability to select proper sites in which cysteine-substitution does not alter protein structure or function

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