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LC-MS Metabolite extracts have been analyzed by either reversed-phase chromatography or hydrophilic interaction chromatography (HILIC), both directly coupled to mass spectrometry (LC-MS/MS)

RasoolMMalikAButtTTAshrafMABRasoolRZahidAet alImplications of advanced oxidation protein products (AOPPs), advanced glycation end products (AGEs) and other biomarkers in the development of cardiovascular diseases

This prevents a rare but serious brain condition called Wernicke's encephalopathy

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The differential diagnosis is broad because symptoms can be due to gastrointestinal (malrotation, gastroparesis), intracranial (intracranial masses, hydrocephaly), or abdominal (renal colic) disorders, or to metabolic (fatty acid oxidation or urea cycle disorders, mitochondrial dysfunction) or drug/toxin (CHS) alterations.77 Laboratory, radiographic, and endoscopic tests detect a substantial number of these differential diagnoses

However, in the CCI + DMSO group, mitochondria were fragmented and appeared as small, dispersed granules (Fig