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CD14 high CD16 monocytes were characterized by high surface expression levels of the CC chemokine receptor type 2 (CCR2), known to be a major regulator of monocyte trafficking to inflammatory sites, while non-classical CD14 low CD16 + monocytes patrol the blood vasculature, being therefore key players to survey local tissue damage (61)

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Natural interventions including antioxidants such as vitamin C and riboflavin , as well as glycation inhibitors such as carnosine and carnitine , may help reduce the risk of cataract formation