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For example, mutations in isocitrate dehydrogenase 1 and 2 ( IDH1/2 ) occur in a subset of acute myeloid leukemia (AML) patients and IDH2 mutant leukemic cells produce elevated levels of the oncometabolite d-2-hydroxyglutarate (D2-HG) (17, 18)

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Then samples were incubated with primary anti-MUC-1 (Servicebio) and anti--actin (Abclonal, Wuhan, Hubei, China) at 4C overnight

In dieser Situation reichen die blichen Vitamin-C-Dosierungen nicht mehr aus, um den Plasmaspiegel wieder zu normalisieren.(118) Die Verabreichung einer hohen Dosis Vitamin C (500 mg, oral oder intravens) vor und nach der Operation kann unter anderem zur Linderung postoperativer Schmerzen von Nutzen sein