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Dkk4 , a key antagonist of the Wnt/-catenin signaling pathway, plays a precise regulatory role in hair follicle development and regeneration ( Lgr6 , a Wnt pathway co-receptor predominantly expressed in HFSCs, enhances Wnt/-catenin signaling to support hair follicle development and regeneration (Snippert et al., 2010

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As the temperature drops over that period of time, weak hydrogen bonds would reform and molecules would rearrange, Katz argues