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Retinoic acid induces matrix Gla protein gene expression in human cells

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Among the 23 genes commonly upregulated in both wild-type and scav-4(L462F) animals by JUb74 diet, we found three lysozymes ( lys-10 , ilys-2 , and ilys-3 ), five innate immune genes ( clec-17 , clec-69 , clec-70 , Y38H6C.23 , and F01D5.3 ), four cytochrome P450 genes ( cyp-13A4, cyp-13A8, cyp-13A9, and cyp-13A12 ), two fatty acid desaturases ( fat-5 and fat-7 ), one acyltransferase ( acl-12 ), and one carnitine O-palmitoyltransferase ( W03F9.4 ) (Figure 6B)

As seen in Figure 4B and D, decreased expression of SQSTM1 in the presence of 0.5 mM palmitate alone was further decreased by addition of DMSO

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