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However, because natural live bacteria lack canonical non-homologous end joining machinery, ZFN-induced DSBs frequently trigger bacterial cell death, severely impeding precise, scarless gene editing in prokaryotic hosts [106]

doi: 10.1016/j.cell.2011.03.002 13 ChanDC

What we care about most, though, are interventional studies, where people are randomized to B12 so we can see what happens, and when we look at those, we find there is no increased fracture risk among those given B12

Fluorescent sensing platform for the detection of p-nitrophenol based on Cu-doped carbon dots

Chitosomal encapsulation enhances the anticancer efficacy of a theobromine analogue: an integrated in Silico and in vitro study