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The following data were extracted in addition to the previously mentioned outcomes: digital object identifier, first author, publication year, countries, centers, study period, study population, sepsis definition, age, gender, PCT protocol, protocol adherence, appropriateness of AB therapy, and exclusion criteria

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10.1056/NEJMoa1705342 185

In addition, BCAA supplementation also reduced the Firmicutes/Bacteroidetes ratio in middle-aged mice (194)

A NF-B-independent function of NIK has also been demonstrated in hepatocytes, in which it promotes insulin resistance and lipid accumulation in a mouse model of metabolic nonalcoholic steatohepatitis (NASH)

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