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In fact, GSH metabolism impairment has been associated with several diseases such as cancer, kwashiorkor, seizure, Alzheimers and Parkinsons disease, liver disease, cystic fibrosis, sickle cell anaemia, acquired immunodeficiency disease syndrome (AIDS), heart attack, stroke, diabetes [8,14,15], several mitochondrial disorders [16], Niemann Pick type C disease [17] and progressive multiple sclerosis [18,19]

36 shows that the biomass of BCF is much more than that of BAC, considering from the calculation above, we can find that for BCF system, biodegradation is in compliance with high matrix kind

Integrating patient-specific genetic and metabolic profiles could also facilitate the design of individualized, multi-target intervention strategies