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PMID 29881591

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Regular monitoring of urine ketones during these conditions can help detect insulin deficiency early, enabling timely intervention

Wilding J, Van Gaal L, Rissanen A, Vercruysse F, Fitchet M

Nexo E, Hoffmann-Lcke E

however, this represents early-phase evidence only, and the mechanistic effects observed in trials including increased energy expenditure and lipolysis via glucagon receptor agonism have not yet been fully characterised in long-term human studies