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And so when they're then exposed to the ischemic stroke, their outcomes are so much better, so much better, than the animals that didn't get the sulforaphane 48 hours before, whatever it was

The most impressive research on the combination of acetyl-l-carnitine and alpha lipoic acid, so far, seems to have been done in rodents, such as: Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress link Acetyl-l-carnitine fed to old rats partially restores mitochondrial function and ambulatory activity (ambulatory activity = movement such as walking or running) link Neuronal mitochondrial amelioration (restoration) by feeding acetyl-L-carnitine and lipoic acid to aged rats link Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: Partial reversal by feeding acetyl-l-carnitine and/or R --lipoic acid link The effect of acetyl-L-carnitine and R--lipoic acid treatment in ApoE4 mouse as a model of human Alzheimers disease link In terms of human studies that combine the two, theyre more limited

Burnham EL, McCord JM, Bose S, Brown LA, House R, Moss M, et al

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Some clinicians argue that the weekly B12 bolus from the compound is perfectly adequate