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(ii) Redetermines the proration factor used in calculating the prepaid shared savings multiplier under paragraph (f)(2)(iii) of this section to account for changes in the ACO's assigned beneficiary population in the benchmark years of the ACO's agreement period in which the ACO receives prepaid shared savings due to the addition and removal of ACO participants or ACO providers/suppliers in accordance with 425.118(b), a change to the ACO's beneficiary assignment methodology selection under 425.226(a)(1), or changes to the beneficiary assignment methodology under subpart E of this part

doi: 10.1002/jcp.26249

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A registered Phase 1 record and very small publications do not establish general safety, effectiveness or an authorised use

[3] Intramuscular injection, or more specifically peri-lesional injection near an injured tendon or joint, has been used in animal models to test whether local delivery produces superior effects compared to systemic dosing