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Addressing these gaps will require integrated structural biology, subcellular proteomics, and preclinical studies to establish a mitochondria-centric, context-dependent framework for ferroptosis regulation

On the population level, an ideal vaccine would limit transmission

In contrast to VDAC and ANT, cyclophillin D has been shown to be a key constituent and determinant of MPT (Nakagawa et al., 2005

LLK, LPK, and pEK all reduced melanin content and tyrosinase activity, with PEK exhibiting the strongest inhibitory effect

In acute leukemia, KMT2A gene rearrangements are linked to more aggressive disease characterized high rates of relapse and very poor prognoses

Schall, T