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Description

Having previously conducted a series of investigations of the oxidative damage theory that did not support it [34-38], we were curious about the life-extending effect of GSH, which is consistent with this theory

Large alpha-synuclein oligomers inhibit neuronal SNARE-mediated vesicle docking

Levels peak in your twenties and decline steadily after

10.1007/s11356-019-07511-x 160 VizsnyiczaiG.FrangipaneG.BianchiS.SaglimbeniF.DellArcipreteD.Di LeonardoR

Additional drugs such as the nerve protective agent olesoxime and the ion channel-targeting neurosteroids have been established promising effect on CIPN in preclinical studies, which, however, are required to be further confirmed in human studies (Table 1 )