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Overexpression of TFRC contributes to the continuous accumulation of ferrous iron and autophagic lysosome-mediated degradation of ferritin, and promotes lipid peroxidation and cell collapse, resulting in ferroptosis-related cell death [37, 38]

In this model, CRTC1 was identified as a direct target of miR-184-3p, suggesting that the loss of this miRNA compromises molecular mechanisms essential for HPA axis homeostasis and affective behavior regulation (Xu et al., 2024)

Stop use & seek medical advice if: You experience any adverse symptoms (contact a physician or licensed, qualified healthcare professional immediately)

GABA binds to two different classes of receptors, the fast-acting ligand gated or ionotropic receptor GABA A and GABA B

Current studies suggest that the pathophysiological mechanisms of EDC involve multiple factors, including chronic inflammation, neurotransmitter imbalance, hypothalamicpituitaryadrenal (HPA) axis dysfunction, and impaired synaptic plasticity (Yan et al., 2025)

This imbalance can lead to cellular damage and has been linked to numerous pathological conditions, including neurodegenerative diseases, cardiovascular disorders, and cancers (Tabnak et al., 2021a)