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reported that in breast cancer cells, Erastin significantly increased the expression of key autophagy-associated proteins, including beclin-1, ATG5, ATG12, and LC3B, while concurrently decreasing levels of the autophagy substrate p62 (50)

Studies suggest that AOXs, such as CoQ10, vitamins C and E, melatonin, NAC, and alpha-lipoic acid (ALA), may improve oocyte quality, enhance endometrial receptivity, and restore hormonal balance by mitigating OS (188, 189)