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Then, there are special situations where first-line treatment may not be successful, as seen in difficult-to-treat AIH (DTT-AIH), AIH associated with cirrhosis and overlap syndrome

Circ Res 100:174190

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# 101320, 1:25) to prevent unspecific binding

Liver regeneration is significantly impaired in TGR5 KO mice compared to wild-type controls, highlighting the protective role of TGR5 in this process