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Vellai, 2021), which in turn inhibits the retrograde response, the pathway which regulates the response to oxidative stress and which is the equivalent of the NF-B pathway in yeast ( Role of metal chelation in the regulation of CBS activity Several compounds identified in our drug screening point toward an important role of metal ion chelation in the regulation of CBS activity, as previously reported ( CBS overexpression in yeast and H 2 S production in HepG2 cells (Ostrakhovitch et al., 2002

Abbreviations 8OHdG 8hydroxydeoxyguanosine AE adverse effect ALT alanine transaminase AST aspartate transaminase BDNF brainderived neurotropic factor BMI body mass index BUN blood urea nitrogen DEXA dualenergy xray absorptiometry DSST digital symbolsubstitution test GlyNAC combination of glycine plus Nacetylcysteine GSH glutathione HbA1c glycosylated hemoglobin hsCRP highsensitivity Creactive protein IL10 interleukin10 IL6 interleukin6 IQR interquartile range MFO mitochondrial fattyacid oxidation MGO mitochondrial glucose oxidation MoCA montreal cognitive assessment MPBR muscle protein breakdown rate OA older adults OxS oxidative stress RBC redblood cell ROS reactiveoxygen species sICAM1 soluble intracellular adhesion molecule 1 sVCAM1 soluble vascularcell adhesion molecule 1 TBARS thiobarbituric acid reducing substances YA young adults 1

Systematic review and meta-analysis: the effect and safety of peritoneal dialysis in patients with end-stage diabetic kidney disease

Neuropharmacology 163 , 107808 (2020)

A.BurcallL.MpandeC.JenkinsN.et al (2010)