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In total, a minimum of 19 cells were analysed per condition and frame

Therefore, it appears that schistosome TGR fulfills all of the major functions of the mammalian TGR, TrxR1, TrxR2, and GR orthologs, emphasizing the importance of the parasite protein, and this alone should make it an attractive target for treatment of schistosomiasis

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& Rucker, E

10.1002/advs.202001549 12 DongY.DongS.LiuB.YuC.LiuJ.YangD.et al (2021)

It is postulated that glutathione inhibits tyrosinase through three primary mechanisms: direct antioxidant activity, chelation of the copper site within tyrosinase via its thiol group, and disruption of tyrosinase's cellular transport to pre-melanosomes