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Ferritinophagy Iron cellular homeostasis could be regulated by two processes: ferritinophagy and ferroptosis

Conversely, if recruited during inflammation, monocytes will exhibit a pro-inflammatory phenotype and produce pro-inflammatory cytokines, commonly referred to as M1 macrophages (classically activated) [88,89,90]

doi: 10.1007/s00210-020-01915-0

It often develops following cutaneous inflammation and is triggered by various stimuli, from inflammatory and autoimmune conditions to iatrogenic causes and mechanical injuries

The remaining part of the complex is B12, known as cobalamin, which helps raise energy levels and can be stored in the liver