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BPC-157 upregulates vascular endothelial growth factor (VEGF) expression, promoting new blood vessel formation and enhancing blood supply to injured tissue in preclinical models

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In preclinical models, the peptide has been linked to angiogenesis, which is the formation of new blood vessels, and to fibroblast activity that drives collagen synthesis in healing tissue

The full-length TrkB isoform is a typical tyrosine kinase wherein homodimerization during ligand binding causes intracellular cross-tyrosine phosphorylations (30)