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Pathophysiology beyond dopaminergic neuronal loss The alpha-synuclein model Alpha-synuclein is a presynaptic neuronal protein whose abnormal aggregation into Lewy bodies leads to disruption in cellular homeostasis and consequently neurodegeneration 7

L-Theanine L-Theanine (-L-glutamylethylamide) is a nonproteinogenic amino acid occurring naturally in tea

However, when the demand for ATP is lower than that for NAD + , this condition may result in damage to the ETC, which in turn may trigger increased O 2 production

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Glis3 regulates transcription of thyroid hormone biosynthetic genes in coordination with other thyroid transcription factors