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Suppressor of cytokine signaling (SOCS) proteins, most notably the SOCS-3, inhibit insulin signaling by preventing IRS protein activation through direct molecular interactions and altered protein stability in metabolically active tissues (165)

#criticalcare #ICUmortality #metabolicacidosis #NEJMtrial #sodiumbicarbonate To view or add a comment, sign in New publication Results from a real-world study, published in Scientific Reports, show 6-month response status predicts 12-month DAPSA remission in adults with PsA receiving guselkumab

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Molecular Detection of Virulence and Carbapenem Resistance Genes in Clinical Isolates of Pseudomonas aeruginosa from Iraqi Hospitals