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GPi output is inhibitory on the glutamatergic thalamic projections

This is particularly concerning in the context of plantar fasciitis, where the plantar fascia itself could be weakened, potentially worsening the condition

& Lynch, R

Derks TGJ, et al

This requirement for simultaneous activating triggers makes the NMDA receptor ideally suited to be a coincidence detector, responding only when presynaptic and postsynaptic neurons are simultaneously activated