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Excessive iron accumulation in the brain intensifies oxidative stress, amplifies lipid peroxidation, and promotes ferroptosis, thereby accelerating neuronal degeneration (Zhang et al., 2024)

Published Parkinson's research used 3x/week IV infusions for defined study periods

Their findings indicated a reduction in GlyT1 expression in the thalamus and subthalamus, suggesting that this downregulation may act as a compensatory defense mechanism