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The basics of brain development

315 Astrocytes in AxD show profound alterations in morphology and function, with evidence of abnormal glutamate clearance, substantial cell stress in the form of upregulated expression of heat shock protein, MAPK pathways, JNK and p38 kinases, as well as increased autophagy and proteasomal activity

Gil, C., Ramos-Miras, J., Roca-Prez, L., & Boluda, R

Song Y, Wang X, Sun Y, Yu N, Tian Y, Han J, et al

For cation-exchange chromatography, phosphate buffer (10 to 50 mM) between pH 5.0 and 7.5 should be tried first

311 Such findings point towards different roles and different effects of reactive astrocytes at different times during the progression of autoimmune inflammation and suggest that different therapeutic approaches involving astrocytes may be required at different times