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This weakens zonules, leading to bilateral lens dislocation in most cases, prevalent from infancy to later years

The half maximal inhibitory concentration (IC50) of zebularine is approximately seven-fold higher than that of 5AC (120 M vs 17.4 M, respectively) in human bladder cancer T24 cells, with a degradation rate lower than 7% within 48 h ( Zebularine also inhibits cytidine deaminase, which confers resistance to nucleoside analogs (Zhang et al., 2021) and liver HepG2 (Zhou et al., 2011)

Regarding assemblies, the 1 NF characteristic phasor completely disappeared at 5 min, indicating potential disassembly

GAPDH, 18S rRNA, or a synthetic fragment of GFP mRNA (89 bases) was used as an internal control for data normalization

Ferroptosis, by contrast, is a distinct form of PCD driven by iron-dependent lipid peroxidation, leading to membrane damage and cell death (7)

Buildup of 5-oxoproline in the urine (5-oxoprolinuria)